Group leader: Giancarlo Panzica
Skype: Chiama mari_lena88
Born in Tricarico (MT) on 08.06.1988. Italian.
2018. PhD in Neuroscience, University of Turin, Italy.
2013. Master’s Degree in Biology Applied to Biomedicine cum curriculum Neurobiological, University of Pisa, Italy
2011. Bachelor’s Degree in Molecular Biological Sciences, University of Pisa, Italy.
My academic training and research experience have provided me with an excellent background in multiple biological disciplines including molecular biology, neurobiology, neuroendocrinology, and animal behavior. As an undergraduate, I conducted research with Dr. Alessandro Sale, CNR of Pisa, on the fluoxetine treatment as promoter of functional recovery in a rat model of cervical spinal cord injury (Scali et al., 2013, Scientific Reports, 3:2217).
During my PhD, I attended my doctoral studies at the University of Turin in Panzicas’s lab, Laboratory of Neuroendocrinology, University of Turin from 2014 to 2018. My PhD thesis was focused on the study of the distribution of Kisspeptin system within Hypothalamic Paraventricular Nucleus and defining the consequences of early exposure to genistein on several behavioral and neural parameters in mice. My training has centered on the studies of behavioral and hypothalamic neural systems related to reproduction and metabolic regulations. My results have been published in international journals [ M.Marraudino et al., 2019, IJMS, 18;20(10); M.Marraudino et al., 2018, Brain Research, 1;1688:8-14; M. Marraudino et al., 2017, Journal of Anatomy, 230(6):775-786].
After the PhD degree, I became postdoctoral fellows at the Department of Neuroscience, University of Turin, and I’m currently working in my laboratory at the Neuroscience Institute CavalieriOttolenghi (NICO) in Orbassano (TO), under the supervision before of Prof. Giancarlo Panzica, and after of Prof. Stefano Gotti. In these years, I followed several lines of research, contributing significantly to studies on the role of endocrine disruptors. My interest has mainly focused on genistein, and in the estradiol regulation on different brain functions. In addition, during these years, I was committed to developing strong international collaborations, without my supervisors, aimed at studying the morphological distribution of the membrane estrogen receptor, GPER30, whose data have recently been published ( M.Marraudino et al., Neuroendocrinology. 2020 June; R. Llorente, M. Marraudino et al., Frontiers in Endocrinology. 2020 July).
During my doctoral studies and in my years as a postdoc I have acquired a number of laboratory skills, including performing in vitro and in vivo studies, some surgical procedures, preparing tissue samples and processing them by immunohistochemistry, and organizing data for presentation after confocal imaging and counting. I demonstrated my ability both to learn new skills, and to understand the complexity of biological models in vivo.
Academic training and Research experience
1 st January/present. Annual Post Doctoral Fellowship awarded, Umberto Veronesi Foundation, Neuroscience Institute CavalieriOttolenghi (NICO), Orbassano (TO), University of Turin. Supervisor: Prof. Giancarlo PANZICA, Department of Neuroscience ‘Rita Levi Montalcini’, University of Turin, Turin, Italy.
2019/2020. Post Doctoral Fellowship, Department of Neuroscience ‘Rita Levi Montalcini’ University of Turin. Supervisor: Prof. Stefano GOTTI, Department of Neuroscience ‘Rita Levi Montalcini’, University of Turin, Turin, Italy.
2018/2019. Post Doctoral Fellowship, Department of Neuroscience ‘Rita Levi Montalcini’ University of Turin. Supervisor: Prof. Giancarlo PANZICA, Department of Neuroscience ‘Rita Levi Montalcini’, University of Turin, Turin, Italy.
2017. Training stay in the laboratory of Daniela GRASSI, Universidad Europea de Madrid, Basic Biomedical Science, Madrid, Spain.
2016/2017 . Research Scholarships by CRT Foundation (Dep. Neuroscience, University of Turin), ‘Role of pituitary neuropeptides and gonadal hormones in Attention Deficit / Hyperactivity Disorder (ADHD)’ . Supervisor: Dr. Stefano GOTTI.
2016 . Cost Action GNRH Network, Short term Scientific Missions in Madrid, Spain.
January 1 st - March 31th, 2016.Training stay, ‘ The effects of Genistein on neuronal differentiation in vitro’ , in the laboratory of Prof. Luis Miguel GARCIA SEGURA, Cajal Institute, Neuroactive steroids, Madrid (Spain).
2016 . Grant Erasmus+ (Madrid, Spain).
January 15th - July 15th, 2016 . Training stay awarded by Erasmus+ in the laboratory of Prof. Paloma COLLADO, National Distance Education University (UNED), Department of Psychology, Madrid (Spain).
2015 . Cost Action GNRH Network, Short term Scientific Missions.
March 16th - June 3th, 2015.Training stay, ‘ Kisspeptin, NPY and MSH systems, as targets for the action of the obesogenic food compound, genistein ’, in the brain in the laboratory of Dr. Matthieu KELLER, INRA, Neuroendocrinologie des Interactions et Comportements Sexuels, Tours (France).
A.Y. 2019/20, 2020/21 Contract professor of Neuroanatomy and Imaging ; University of Turin, Department of Life Sciences and Systems Biology, degree course of Cellular and Molecular Biology.
A.Y. 2020/21 Teaching assistant of Human Anatomy ; University of Turin - Faculty of Medicine, Department of Surgical Sciences, degree course of “Tecniche Audiometriche”, of “Tecniche Audioprotesiche” and of Neurophysiopathology with Dr. Luca Guglielmo PRADOTTO.
A.Y. 2017/18 to 2020/21 Contract professor of Histology; International College of Osteopathic Medicine (ICOM), Turin, Italy.
European Journal of Histochemistry , November 2021
Brigitta Bonaldo, Antonino Casile, Martina Bettarelli, Stefano Gotti, GianCarlo Panzica, Marilena Marraudino
Group leader: Giancarlo Panzica
Neuroendocrinology , 2020 June 22
Frontiers in Endocrinology , 2020 August 7
Chronic treatment with tributyltin induces sexually dimorphic alterations in the hypothalamic POMC system of adult mice.
Cell Tissue Research
, 4 August 2018
Farinetti A, Marraudino M, Ponti G, Panzica GC, Gotti S