Physiopathology of neural stem cells

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Group leader:  Annalisa Buffo 

Physiopathology of neural stem cells
martina lorenzati

Martina Lorenzati

PostDoc

Tel   +39 011 670 6632
Fax  +39 011 670 5451
e-mail: martina.lorenzati@unito.it

Born in Savigliano (CN) on 30.10.1992 - Italian

Current position
Post Doc Fellow

Education
2021 PhD in Neuroscience, University of Turin, Department of Neuroscience “Rita Levi Montalcini” – Thesis: “Uncovering novel players in oligodendroglia physiopathology and heterogeneity”, Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano (TO)

2016 Master’s Degree in Medical Biotechnology (summa cum laude and honourable mention),
University of Turin, Italy – Thesis: “Role of JNK1 in oligodendrocyte differentiation”,
Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano (TO)

2014 Bachelor’s Degree in Biotechnology (summa cum laude), University of Turin, Italy –
Thesis: “Genomic rearrangements and resistance to target therapy”, IRCCS, Candiolo (TO)

Scientific Societies
Gruppo Italiano per lo Studio della Neuromorfologia (G.I.S.N.); Società Italiana per le Neuroscienze (SINS)

Scientific Interests
My scientific interests include the study of oligodendroglia-neurons crosstalk, the molecular and cellular mechanisms involved in the regulation of heterogeneity and plasticity of oligodendrocyte progenitor cells in health and disease, de-/dis- myelinating diseases and the molecular mechanisms involved in the process of re-myelination after damage.

News

Not all oligodendrocyte precursors are created equal

Nature Communication , 28 April 2022

Molecular and functional heterogeneity in dorsal and ventral oligodendrocyte progenitor cells of the mouse forebrain in response to DNA damage. 

Enrica Boda, Martina Lorenzati, Roberta Parolisi, Brian Harding, Gianmarco Pallavicini, Luca Bonfanti, Amanda Moccia, Stephanie Bielas, Ferdinando Di Cunto, Annalisa Buffo

5 May 2022

Allele-specific silencing as treatment for gene duplication disorders: proof-of-principle in autosomal dominant leukodystrophy.

Brain , 29 May 2019
Giorgio E, Lorenzati M, Rivetti di Val Cervo P, Brussino A, Cernigoj M, Della Sala E, Bartoletti Stella A, Ferrero M, Caiazzo M, Capellari S, Cortelli P, Conti L, Cattaneo E, Buffo A, Brusco A.

24 June 2019