Gruppo guidato da Carola Eva
Carola Eugenia Eva
Tel +39 011 670 6608
Fax +39 011 236 7718
Date and place of Birth: 21 July 1957 in Torino, Italy.
Department of Neuroscience, University of Torino; Neuroscience Institute Cavalieri Ottolenghi (NICO); Neuroscience Institute of Torino; Consorzio INN.
Full professor of Pharmacology, Medical School, University of Turin.
Education and Training
1981 Doctoral, Summa cum Laude, University of Turin, Faculty of Science MFN
1988 Ph.D in Pharmacology and Toxicology.
Employment and research experience
. 1982: National Institute of Mental Health, Washington D.C. , USA.
. 1983-1985: Visiting Fellow, National Institute of Mental Health, Washington D.C. , USA.
. 1985-1986: Research associate, School of Medicine, Georgetown University, Washington D.C., USA.
. 1987- 1992: Postdoctoral Fellow, Medical School, University of Turin.
. 1989- 1990: Centrum for Molecular Biology Heidelberg, Heidelberg University, Germany
. 1992-1998: Research Associate, Medical School, University of Turin.
. 1998- 2004: Associate Professor of Pharmacology, Medical School, University of Turin.
. 2004-present: Full professor of Pharmacology, Medical School, University of Turin.
. From 2010 the laboratory has moved to the NICO: Neuroscience Institute Cavalieri-Ottolenghi, Cavalieri-Ottolenghi Foundation, Orbassano.
Professor of Pharmacology at the Faculty of Medicine, Psychology, Biotechnology; in the schools of Specialization in Psychiatry, Human genetic, Pediatric Neuropsychiatry, Internal Medicine; tutor in the School of Doctorate in Medicine and Experimental Therapy
-Dr. Gavin Bewick, Division of Diabetes & Nutritional Sciences, School of Biomedical sciences, King's College London,London, UK.
-Dr. Eric Grouzmann, Centre Hospitalier Universitaire Vaudois, Département des Laboratoires, Laboratoire des Catécholamines et Peptides, Hôpital Beaumont, Lausanne, Switzerland.
-Dr Jessica Kwok, Faculty of Biological Sciences, University of Leeds, UK.
-Dr. Ralf Ritcher, Parque tecnológico de San Sebastián, San Sebastian, Spain.
-Dr. Roland Schuele, Department of Urology, Center for Clinical Research, University Freiburg Medical Center, Freiburg, Germany.
-Dr. Rolf Sprengel, Max Plank Institute for Medical Research, Heidelberg, Germany.
-Dr. Janice Urban, Rosalind Franklin University of Medicine and Science, Physiology & Biophysics, North Chicago, Illinois, USA.
-Dr. Stefano Vicini, Department of Physiology and Biophysics, Georgetown University School of Medicine, Washington DC, USA.
-Dr. Giovanni Biggio, Dept. of Life and Environmental Sciences, Section of Neuroscience, University of Cagliari.
-Dr. Annalisa Buffo, Neuroscience Institute Cavalieri Ottolenghi, Dept. of Neuroscience, University of Torino.
-Dr. Daniela Carulli, Neuroscience Institute Cavalieri Ottolenghi, Dept. of Neuroscience, University of Torino.
-Dr. Adriana Maggi, Center of Excellence on Neurodegenerative Diseases and Department of Pharmacological and Biomolecular Sciences, University of Milan
-Dr. Enzo Nisoli, Dpt of Medical Biotechnology and Translational Medicine, Center for Study and Research on Obesity, University of Milan
-Dr. Paola Palanza, Dept of Evolutionary and Functional Biology, University of Parma.
-Dr. Mariangela Serra, Dept. of Life and Environmental Sciences, Section of Neuroscience, University of Cagliari.
Scientific Research Programs of the University of Torino / Compagnia di San Paolo Foundation 2015-2017
CRT Foundation 2014-2016
Scientific Research Programs of Relevant National Interest of MIUR, 2013-2016.
Scientific research in biomedical field, Cariplo Foundation, n. 2013-0786, 2014-2017.
Scientific Research Programs of Relevant National Interest of MIUR, 2010 -2012.
Neuroscience Program. Compagnia di San Paolo Foundation, Turin, Italy, 2009-2012
Scientific Research Programs of Relevant National Interest of MIUR, 2008 -2010
Carola Eva is internationally recognized for her studies on NPY e Y1 receptor that were performed by using biomolecular, histochemical, image analysis, behavioural and pharmacological techniques. In particular: cloning of 7 TM receptors, Y1 receptor, Y1 receptor gene, regulation of Y1 receptor gene transcription (NF-kappaB, estrogens); role of the Y1 receptor in the regulation of the feeding behavior; interaction between GABA, NPY and neuroactive steroids during pregnancy, stress response and ethanol consume.
The research group coordinated by Carola Eva has generated transgenic mice and conditional knockout mice for the murine Npy1r gene that represent innovative models to study the role of Y1R in anxiety, stress response and energy homeostasis.
The results of Dr. Eva’s studies are published in 69 publications, 49 listed in PUB Med (1141 citations, H-index 18, mean IF 5,03).
I video di TorinoMedica
intervista a Carola Eva
Mamma, conosci il gene Npyr1?
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Our spinoff provides scientific expertise, animal models, equipment and facilities to pharmaceutical, biotechnology, and medical device Companies and to Research Centers for proof–of-concept or pilot in vivo studies.
Maschi e femmine: uno studio sui meccanismi che regolano le differenze sessuali dell’attività cerebrale
Le differenze di sesso influenzano il cervello, il comportamento, le funzioni metaboliche e contribuiscono alla vulnerabilità alle malattie. Tuttavia, i meccanismi alla base delle differenze sessuali dell'attività cerebrale sono ancora poco noti.
Le nostre ricercatrici del gruppo di Neuropsicofarmacologia hanno analizzato l'inattivazione condizionale del gene Npy1r nei topi, osservando che induce differenze legate al sesso delle funzioni metaboliche e comportamentali.