Adult neurogenesis

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Group leader:  Luca Bonfanti and  Paolo Peretto

silvia demarchis

Silvia de Marchis

Associate Professor of Comparative Anatomy and Cytology


Tel + 39 11 6706605 - 4674
Fax + 39 11 6705451

Curriculum Vitae

Born in Turin on 14.09.1966. Italian.
1993. 6 months internship at the Laboratory of Neuroendocrinology Univ. Rouen, France. Erasmus Program.
1994. Honor degree in Biology 110/110, University of Turin, Italy.
1994-1995. Practical laboratory training at the Dept. of Animal Biology, Univ. of Turin, Italy.
2000. PhD in Neuroendocrinology, University of Milan, Italy.
2000. 1 year Post-doctoral research contract. Dept. of Animal Biology, Univ. of Turin, Italy.
2000. 4 months stage at the Department of Neuroanatomy, Univ of Baltimore, USA.
2001-2014: Assistant Professor (BIO/06) at the Department of Human and Animal Biology (now Life Sciences and System Biology), University of Turin, Italy.
2002. 4 months research contract at the Dept. of Neuranatomy; University of Baltimore, USA.
2015. Associate Professor of Comparative Anatomy

6 months fellowship (Erasmus Program 1993);
4 years "Dottorato di ricerca" (PhD at the University of Milan, 1996-1999);
Short mobility grant (CNR, 1997);
Short mobility grant (The Biotecnology Foundation, 1997);
1 year assegno di ricerca ( University of Turin, 2000)

Guest Editor in 'Special Issues' on peer reviewed journals:
Cellular Imaging and Emerging Technologies for Adult Neurogenesis Research (2012) Front. Neurosci.

Associate Editor:
Frontiers in Neurogenesis

Guest referee for international scientific journals:  ? 
PLoS ONE; Neuroscience; J. Comp. Neurol.; J. Neurosci.; Eur. J. Neurosci.; Exp. Neurol.; J. Neurochem.; Neurobiol. Dis.; Brain Res.; Brain Res. Bull.; Int. J. Dev. Neurosci.; Neurosci. Lett.; J. Neurosci. Res.; Front. Neuroscience; Brain Structure and Function; Journal of Visualized experiments (JoVE)

Scientific Societies:
Società Italiana di Neuroscienze (S.I.N.S.); Society for Neurosciences (USA); European Chemioreceptor Research Organization (ECRO).

Membership in research centers:
Neuroscience Institute Cavalieri Ottolenghi (NICO, Orbassano, Turin);

Membership in research networks:  
Istituto Nazionale di Neuroscienze (INN); Neuroscience Institute Turin (NIT); Progetto NEUROTRANSPLANT; Centro di Ecellenza superfici ed interfasi nanostrutturate (NIS)

Reviewer in international grant projects:
Medical Research Council (UK) – Research Grants applications

PhD program
Tutor for the "PhD course in Neuroscinece" University of Turin.

PhD students:
Donatella Garzotto; Simona Gribaudo; Sara Bonzano.

Member in final PhD thesis evaluation committee:
- PhD in co-sharing Italy-France, Dr. Samuele Chiaramello: Brain Derived Neurotrophic Factor
(BDNF) et régulation de la neurogenèse dans le système olfactif de la souris adulte (Lyon, 2008)
- Dr. Sebastien Sultan: "Régulation par l'apprentissage de la neurogenèse adulte dans le bulbe olfactif et rôle des nouveaux neurones". ?(Lyon, 2010).
- Dr. Giulia Pregno: "Organization and interaction of synaptic adhesion systems at GABAergic synapses" (Turin 2013).

Main invited conferences:
- Developmental mechanisms regulating neural diversity: intrinsic and extrinsic factors in the generation of inhibitory interneuron subtypes. Meeting of the ISIS Euro-Mediterranean Master in Neuroscience and Biotechnology Alexandria University, Egypt (2011)
- Neurogenesis in the adult olfactory bulb: from stem cells to integrated interneurons. Symposium Olfactory Information Processing, (Heidelberg, 2007).
- Modulation of the olfactory input in adult mice regulates survival and phenotype of newly generated periglomerular cells. Symposium: "Plasticité des interneurones bulbaires", Université Claude Bernard, UMR 5020, (Lyon, 2007).

Invited seminars:
- HGF/Met signaling regulates neuroblast migration in the SVZ-OB system. Host Chichung Lie Helmholtz Zentrum, (Munich 2008).
- Neurogenesis and cell differentiation in the SVZ-OB system. Host Carlos Dotti Fondazione Cavalieri Ottolenghi, Orbassano, (Torino 2006).
- Age dependent specification of olfactory bulb interneurons. TIGEM, host Michèle Studer (Napoli 2005)

Scientific collaborations:
Dr. Michèle Studer, INSERM U636, Nice Sophia Antipolis, France;
Prof. Jeroen Pasterkamp, University Medical Center, Utrecht, The Netherlands;
Prof. Vincenzo Cestari, Università la Sapienza, Roma, Italia


Neuron-Astroglia Cell Fate Decision in the Adult Mouse Hippocampal Neurogenic Niche Is Cell-Intrinsically Controlled by COUP-TFI In Vivo

Cell Reports , 10 July 2018
S Bonzano, I Crisci, A Podlesny-Drabiniok, Chiara Rolando, W Krezel, M Studer, S De Marchis

13 July 2018

Opposite-sex attraction in male mice requires testosterone dependent regulation of adult olfactory bulb neurogenesis

Scientific Reports , October 2016
Schellino R, Trova S, Cimino I, Farinetti A, Jongbloets BC, Pasterkamp RJ, Panzica G, Giacobini P, De Marchis S, Peretto P.

25 January 2017