J. Kwok, University of Cambridge (UK)

Share on
Event date: 23/02/2015

Monday, 23th February - h 14:30
Seminars room, NICO

Molecular fine-tuning in the perineuronal nets orchestrate plasticity and repair in the CNS
Jessica Kwok
John van Geest Centre for Brain Repair, University of Cambridge (UK)

PNNs are a layer of macromolecular complexes in which extracellular matrix molecules, polysaccharides (such as chondroitin sulphate proteoglycans and hyaluronan) and soluble proteins, form a compact layer of aggregates and anchor onto the neuronal surface. Using biochemical, cell biology, together with functional studies, we have established the core molecular and structural components of the PNNs and demonstrated that manipulation of PNNs effectively increases plasticity in the adult CNS.

Host: Daniela Carulli

download pdf

Events & Meetings

27 february 2020


University of Turin, Italy   
The Workshop is aimed at PhD students and young Postdocs with the goal to promote a thorough understanding of the functions of glial cells in health and disease. The program includes lectures on the newest conceptual advancements and methodological approaches in the study of glial cells in synaptic functions, development and CNS diseases.

Deadline for registration: December 23, 2019.

29 november 2019

NICO Progress Report - INN Open Neuroscience Forum 2019

Our young researchers present their work to collegues. From January to December, every two weeks, on friday at 2:00 pm
Seminars Room, NICO

14 november 2019

BraYn 2019 Milan, 14-16 November

The main goal of the BraYn initiative is to organize a scientific conference involving different laboratories across Italy and Europe where young researchers, especially PhD students and junior postdocs, can share their knowledge, skills and ideas to establish new collaborations between different research groups.