Friday, June 14th - h 2:00 p.m.
Seminars Room, NICO
Neuroscience Institute Cavalieri Ottolenghi
Regione Gonzole 10, Orbassano (TO)
Brain functional shapes: how topology characterizes healthy and altered brain function
Topology, one of the oldest branches of mathematics, captures the concept of shape for spaces of arbitrary type and dimension. This allows to adopt some of its concepts to characterize and compare how the brain activity evolves and restructures itself.
In the talk, I will briefly introduce two topological techniques, persistent homology and Mapper, to illustrate what novel insights these new descriptive paradigms yield for the analysis of how the brain works at the functional, structural and genetic level.
As case studies, I will show how psychedelic drugs alter the shape of the landscape of brain activity leading to a radical reorganization of the hierarchies of functional circuits. I will also compare these results with those obtained in treated and untreated bipolar subjects, and during simple mental imagery experiments. Finally, using brain gene expression data, I will briefly describe recent work on the construction of a topological genetic skeleton highlighting differences in structure and function of different genetic pathways within the brain.
Host: Ferdinando Di Cunto
Events & Meetings
University of Turin, Italy
The Workshop is aimed at PhD students and young Postdocs with the goal to promote a thorough understanding of the functions of glial cells in health and disease. The program includes lectures on the newest conceptual advancements and methodological approaches in the study of glial cells in synaptic functions, development and CNS diseases.
Deadline for registration: December 23, 2019.
Our young researchers present their work to collegues. From January to December, every two weeks, on friday at 2:00 pm
Seminars Room, NICO
The main goal of the BraYn initiative is to organize a scientific conference involving different laboratories across Italy and Europe where young researchers, especially PhD students and junior postdocs, can share their knowledge, skills and ideas to establish new collaborations between different research groups.