Physiopathology of neural stem cells

Share on

Group leader:  Annalisa Buffo 

Physiopathology of neural stem cells

Publications

2018

Cerrato V, Parmigiani E, Figueres-Oñate M, Betizeau M, Aprato J, Nanavaty I, Berchialla P, Luzzati F, de'Sperati C, López-Mascaraque L, Buffo A. Multiple origins and modularity in the spatiotemporal emergence of cerebellar astrocyt eheterogeneity (2018). PLoS Biol. 2018 Sep 27;16(9):e2005513. doi:10.1371/journal.pbio.2005513

Cerrato V, Mercurio S, Leto K, Fucà E, Hoxha E, Bottes E, Pagin M, Milanese M, Chew-Yee Ngan, Concina G, Ottolenghi S, Chia-Lin Wei, Bonanno G, Pavesi G, Tempia F, Buffo A and Nicolis KS.  Sox2 conditional mutation in mouse causes ataxic symptoms, cerebellar vermis hypoplasia, and postnatal defects of Bergmann glia   (2018) Glia . 2018 May 6. doi: 10.1002/glia.23448

Bertero A, Liska A, Pagani M, Parolisi R, Masferrer ME, Gritti M, Pedrazzoli M, Galbusera A, Sarica A, Cerasa A, Buffelli M, Tonini R, Buffo A, Gross C, Pasqualetti M, Gozzi A. Autism-associated 16p11.2 microdeletion impairs prefrontal functional connectivity in mouse and human. Brain. 2018 May 2. doi: 10.1093/brain/awy111.

Carulli D. Perineuronal Nets: A Mechanism to Control Brain Plasticity. The Scientist. April 1, 2018

Prada I, Gabrielli M, Turola E, Iorio A, D'Arrigo G, Parolisi R, De Luca M, Pacifici M, Bastoni M, Lombardi M, Legname G, Cojoc D, Buffo A, Furlan R, Peruzzi F, Verderio C. Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations. Acta Neuropathol. 2018 Apr;135(4):529-550. doi: 10.1007/s00401-017-1803-x. Epub 2018 Jan 4.

2017

Garello F, Pagoto A, Arena F, Buffo A, Blasi F, Alberti D, Terreno E. MRI visualization of neuroinflammation using VCAM-1 targeted paramagnetic micelles. Nanomedicine. 2017 Nov 8. pii: S1549-9634(17)30181-8. doi: 10.1016/j.nano.2017.10.002.

Boda E, Nato G, Buffo A. Emerging pharmacological approaches to promote neurogenesis from endogenous glial cells. Biochem Pharmacol. 2017 Oct 1;141:23-41. doi: 10.1016/j.bcp.2017.06.129.

Azzalin A, Nato G, Parmigiani E, Garello F, Buffo A, Magrassi L. Inhibitors of GLUT/SLC2A Enhance the Action of BCNU and Temozolomide against High-Grade Gliomas. Neoplasia. 2017 Apr;19(4):364-373. doi: 10.1016/j.neo.2017.02.009.

Kempf A, Boda E, Kwok JCF, Fritz R, Grande V, Kaelin AM, Ristic Z, Schmandke A, Schmandke A, Tews B, Fawcett JW, Pertz O, Buffo A , Schwab ME. Control of Cell Shape, Neurite Outgrowth, and Migration by a Nogo-A/HSPG Interaction. Dev Cell. 2017 Oct 9;43(1):24-34.e5. doi: 10.1016/j.devcel.2017.08.014. Epub 2017 Sep 21.

Fucà E, Guglielmotto M, Boda E, Rossi F, Leto K, Buffo A. Preventive motor training but not progenitor grafting ameliorates cerebellar ataxia and deregulated autophagy in tambaleante mice . Neurobiol Dis. 2017 Feb 22.

Faedo A, Laporta A, Segnali A, Galimberti M, Besusso D, Cesana E, Belloli S, Moresco RM, Tropiano M, Fucà E, Wild S, Bosio A, Vercelli AE, Biella G, Cattaneo E.   Differentiation of human telencephalic progenitor cells into MSNs by inducible expression of Gsx2 and Ebf1 . Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1234-E1242.

Joshi P, Gabrielli M, Ponzoni L, Pelucchi S, Stravalaci M, Beeg M, Mazzitelli S, Braida D, Sala M, Boda E, Buffo A, Gobbi M, Gardoni F, Matteoli M, Marcello E, Verderio C. Fingolimod Limits Acute Aβ Neurotoxicity and Promotes Synaptic Versus Extrasynaptic NMDA Receptor Functionality in Hippocampal Neurons. Sci Rep. 2017 Jan 30;7:41734. doi: 10.1038/srep41734

2016

Pellegrino RM, Boda E, Montarolo F, Boero M, Mezzanotte M, Saglio G, Buffo A, Roetto A. Transferrin Receptor 2 Dependent Alterations of Brain Iron Metabolism Affect Anxiety Circuits in the Mouse. Sci Rep. 2016 Aug 1;6:30725. doi: 10.1038/srep30725.

Leto K, Arancillo M, Becker EBE, Buffo A, Chiang C, Ding B, Dobyns WB, Dusart I,  Haldipur P, Hatten ME, Hoshino M, Joyner AL, Kano M, Kilpatrick DL, Koibuchi N, Marino S, Martinez S, Millen KJ, Millner TO, Miyata T, Parmigiani E, Schilling K, Sekerková G, Sillitoe RV,  Sotelo S, Uesaka N, Wefers A, Wingate RJT, Hawkes R (2015)  Consensus Paper: Cerebellar Development . Cerebellum. PMID: 26439486

De Luca A, Cerrato V, Fucà E, Parmigiani E, Buffo A, Leto K (2015) Sonic hedgehog patterning during cerebellar development . Cellular and Molecular Life Sciences DOI: 10.1007/s00018-015-2065-1

2015

Cupolillo D, Hoxha E, Faralli A, De Luca A, Rossi F, Tempia F, Carulli D (2015) Autistic-like traits and cerebellar dysfunction in Purkinje cell  PTEN  knock-out mice . Neuropsychopharmacology

Parmigiani E, Leto K, Rolando C, Figueres-Oñate M, López-Mascaraque L, Buffo A, Rossi F (2015)  Heterogeneity and Bipotency of Astroglial-Like Cerebellar Progenitors along the Interneuron and Glial Lineages .  J Neurosci 35:7388-7402. 

De Luca A, Parmigiani E, Tosatto G, Martire S, Hoshino M, Buffo A, Leto K, Rossi F (2015) Exogenous Sonic hedgehog modulates the pool of GABAergic interneurons during cerebellar development . Cerebellum 14:72-85.

Nato G, Caramello A, Trova S, Avataneo V, Rolando C, Taylor V, Buffo A, Peretto P, Luzzati F (2015)  Striatal astrocytes produce neuroblasts in an excitotoxic model of Huntington's disease . Development 142:840-845. 

Boda E, Di Maria S, Rosa P, Taylor V, Abbracchio MP, Buffo A (2015) Early phenotypic asymmetry of sister oligodendrocyte progenitor cells after mitosis and its modulation by aging and extrinsic factors. Glia 63:271-286.

Vazquez-Sanroman D, Carbo-Gas M, Leto K, Cerezo-Garcia M, Gil-Miravet I, Sanchis-Segura C, Carulli D, Rossi F, Miquel M. (2015) Cocaine-induced plasticity in the cerebellum of sensitised mice . Psychopharmacology. PMID: 26482898

Oohashi T, Edamatsu M, Bekku Y, Carulli D. (2015) The hyaluronan and proteoglycan link proteins: Organizers of the brain extracellular matrix and key molecules for neuronal function and plasticity. Exp Neurol. pii: S0014-4886(15)30092-3. doi:10.1016/j.expneurol.2015.09.010. PMID: 26387938

Faralli A, Dagna F, Albera A, Bekku Y, Oohashi T, Albera R, Rossi F, Carulli D. (2015) Modifications of perineuronal nets and remodelling of excitatory and inhibitory afferents during vestibular compensation in the adult mouse . Brain Struct Funct. PMID: 26264050

Vazquez-Sanroman D, Leto K, Cerezo-Garcia M, Carbo-Gas M, Sanchis-Segura C, Carulli D, Rossi F, Miquel M. (2015) The cerebellum on cocaine: plasticity and metaplasticity . Addict Biol. 20:941-55.