Nerve regeneration

Share on

Group leader:  Stefano Geuna




Ronchi G, Cillino M, Gambarotta G, Fornasari BE, Raimondo S, Pugliese P, Tos P, Cordova A, Moschella F, Geuna S. Irreversible changes occurring in long-term denervated Schwann cells affect delayed nerve repair. J Neurosurg. 2017 Jan 6:1-14. doi: 10.3171/2016.9.JNS16140. [Epub ahead of print]

Ribeiro J, Caseiro AR, Pereira T, Armada-da-Silva PA, Pires I, Prada J, Amorim I, Leal Reis I, Amado S, Santos JD, Bompasso S, Raimondo S, Varejão AS, Geuna S, Luís AL, Maurício AC. Evaluation of PVA biodegradable electric conductive membranes for nerve regeneration in axonotmesis injuries: the rat sciatic nerve animal model. J Biomed Mater Res A. 2017 Jan 12. doi: 10.1002/jbm.a.35998. [Epub ahead of print]

Carriel V, Campos A, Alaminos M, Raimondo S, Geuna S. Staining Methods for Normal and Regenerative Myelin in the Nervous System. Methods Mol Biol. 2017;1560:207-218. doi: 10.1007/978-1-4939-6788-9_15.

Onger ME, Kaplan S, Deniz ÖG, Altun G, Altunkaynak BZ, Balcı K, Raimondo S, Geuna S. Possible promoting effects of melatonin, leptin and alcar on regeneration of the sciatic nerve. J Chem Neuroanat. 2017 Feb 3;81:34-41. doi: 10.1016/j.jchemneu.2017.02.003. [Epub ahead of print]

Mazzara PG, Massimino L, Pellegatta M, Ronchi G, Ricca A, Iannielli A, Giannelli SG, Cursi M, Cancellieri C, Sessa A, Del Carro U, Quattrini A, Geuna S, Gritti A, Taveggia C, Broccoli V. Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells. Nat Commun. 2017 Feb 7;8:14088. doi: 10.1038/ncomms14088.


Meyer C, Stenberg L, Gonzalez-Perez F, Wrobel S, Ronchi G, Udina E, Suganuma S, Geuna S, Navarro X, Dahlin LB, Grothe C, Haastert-Talini K. Chitosan-film enhanced chitosan nerve guides for long-distance regeneration of peripheral nerves. Biomaterials. 2016 Jan;76:33-51. doi: 0.1016/j.biomaterials.2015.10.040.

Papalia I, Magaudda L, Righi M, Ronchi G, Viano N, Geuna S, Colonna MR. Epineurial Window Is More Efficient in Attracting Axons than Simple Coaptation in a Sutureless (Cyanoacrylate-Bound) Model of End-to-Side Nerve Repair in the Rat Upper Limb: Functional and Morphometric Evidences and Review of the Literature. PLoS One. 2016 Feb 12;11(2):e0148443. doi: 10.1371/journal.pone.0148443.

Fregnan F, Ciglieri E, Tos P, Crosio A, Ciardelli G, Ruini F, Tonda-Turo C, Geuna S, Raimondo S. Chitosan crosslinked flat scaffolds for peripheral nerve regeneration. Biomed Mater. 2016 Aug 10;11(4):045010. doi: 10.1088/1748-6041/11/4/045010.

Gnavi S, Fornasari BE, Tonda-Turo C, Laurano R, Zanetti M, Ciardelli G, Geuna S. In vitro evaluation of gelatin and chitosan electrospun fibers as artificial guide in peripheral nerve repair: a comparative study. J Tissue Eng Regen Med. 2016 Nov 12. doi: 10.1002/term.2351. [Epub ahead of print]

Fornasari BE, El Soury M, De Marchis S, Perroteau I, Geuna S, Gambarotta G. Neuregulin1 alpha activates migration of neuronal progenitors expressing ErbB4. Mol Cell Neurosci. 2016 Oct 27. pii: S1044-7431(16)30206-8. doi: 10.1016/j.mcn.2016.10.008. [Epub ahead of print]

Geuna S, Raimondo S, Fregnan F, Haastert-Talini K, Grothe C. In vitro models for peripheral nerve regeneration. Eur J Neurosci. 2016 Feb;43(3):287-96. doi: 10.1111/ejn.13054. Epub 2015 Sep 28. Review. PubMed PMID: 26309051. IF 2,975 Q2
Tos P, Crosio A, Pellegatta I, Valdatta L, Pascal D, Geuna S, Cherubino M. Efficacy of anti-adhesion gel of carboxymethylcellulose with polyethylene oxide on peripheral nerve: Experimental results on a mouse model. Muscle Nerve. 2016 Feb;53(2):304-9. doi: 10.1002/mus.24739. Epub 2015 Aug 8. PubMed PMID: 26082205. IF 2,713 Q2

Ronchi G, Haastert-Talini K, Fornasari BE, Perroteau I, Geuna S, Gambarotta G. The Neuregulin1/ErbB system is selectively regulated during peripheral nerve degeneration and regeneration. Eur J Neurosci. 2016 Feb;43(3):351-64. doi: 10.1111/ejn.12974. Epub 2015 Jul 8. PubMed PMID: 26061116. IF 2,975 Q2

Shapira Y, Tolmasov M, Nissan M, Reider E, Koren A, Biron T, Bitan Y, Livnat, M, Ronchi G, Geuna S, Rochkind S. Comparison of results between chitosan hollow tube and autologous nerve graft in reconstruction of peripheral nerve defect: An experimental study. Microsurgery. 2016 Nov;36(8):664-671. doi: 10.1002/micr.22418. Epub 2015 Apr 22. PubMed PMID: 25899554. IF 2,054 Q2

Meyer C, Wrobel S, Raimondo S, Rochkind S, Heimann C, Shahar A, Ziv-Polat O, Geuna S, Grothe C, Haastert-Talini K. Peripheral Nerve Regeneration Through Hydrogel-Enriched Chitosan Conduits Containing Engineered Schwann Cells for Drug Delivery. Cell Transplant. 2016;25(1):159-82. doi: 10.3727/096368915X688010. Epub 2015 Apr 14. PubMed PMID: 25876520. IF 3,427 Q3