Thursday, 11th May - h 2:00 p.m.
Seminars Room, NICO
Gene Regulation of Functional Brain Networks
It is well known that gene expression patterns exhibit strong correlation with functionally-coupled resting state networks of the human cortex, however little is known on the regulatory program leading to the establishment of these network-specific transcriptional signatures.
In this talk I will discuss a few attempts to shed light on this issue. I will discuss in particular the case of the Default-mode Network and of the Somatosensory Network, showing how to construct a robust set of transcription factors which are likely to control the gene expression program of these networks. As a major result of this analysis I will show that a special role in this regulatory program is played by the the epigenetic layer of regulation and in particular by the PolyComb complex.
Moreover, I will also show that a remarkably similar regulatory program controls transcriptional signatures in corresponding resting-state networks of the mouse brain.
Host: Ferdinando Di Cunto
Events & Meetings
University of Turin, Italy
The Workshop is aimed at PhD students and young Postdocs with the goal to promote a thorough understanding of the functions of glial cells in health and disease. The program includes lectures on the newest conceptual advancements and methodological approaches in the study of glial cells in synaptic functions, development and CNS diseases.
Deadline for registration: December 23, 2019.
Our young researchers present their work to collegues. From January to December, every two weeks, on friday at 2:00 pm
Seminars Room, NICO
The main goal of the BraYn initiative is to organize a scientific conference involving different laboratories across Italy and Europe where young researchers, especially PhD students and junior postdocs, can share their knowledge, skills and ideas to establish new collaborations between different research groups.