Brain development and disease

Share on

Group leader:  Alessandro Vercelli

brain-development_vercelli
Silvia de la Morena Saavedra

Silvia de la Morena Saavedra

Fellowship recipient

Contacts:

Tel  +39 011 670 6632
Fax +39 011 670 5451

Email: Silvia.delamorenasaa@unito.it

Date of birth: 10/06/1998 
Nationality: Spanish

Education

01/09/2016 – 20/07/2020 Bachelor’s Degree in Biology , Universidad Autónoma de Madrid (UAM).

Thesis title: “Influence of VHL gene expression on clear cell renal cell carcinomas (ccRCC).” Biomedicine Department.The aim of the thesis was to study the effects of several drugs, specifically Beta adrenergic blocking drugs (propranolol and ICI, in vitro using Clear Cell Renal Cell Carcinoma (ccRCC) primary cultures of VHL patients.

Supervisors: Maria Luisa Botella and Angel Cuesta.

01/09/2020 – 02/09/2021 Master’s Degree in Biomolecules and Cell Dynamics ,

Universidad Autónoma de Madrid (UAM).

Thesis title: “Characterization of genetic and molecular mechanisms that prevent the activationof the apoptotic pathway in glial cellsand neuroblasts when exposed to ionizing gradiation.” The main goal was to explore the possibility of intrinsic mechanisms thatmight attenuate radiation-induced apoptosis in glial cells, what turns out to be one of theunderlying causes of the Glioblastoma Multiforme (GMB) resistance to radiation.
Supervisor: Antonio Baonza

Work experience

01/09/2019 – 01/09/2020 Research and Development Internship , Center for Biological Research (CIB-CSIC).
Study of the molecular mechanisms leading to thedevelopment of two rare diseases: Hereditary Hemorrhagic Telangiectasia (HHT) and Von Hippel-Lindau Syndrome (VHL), being the main objective to find a pharmacological treatment.

01/09/2020 – 01/09/2021 Research and Development Internship , Molecular Biology Center Severo Ochoa (CBMSO-CSIC).
Study of the regenerative response mechanisms of glial cells and neuroblasts under diverse kinds of stress.

Current position

03/09/2021 – currently Fellowship recipient at Neuroscience Institute Cavalieri Ottolenghi (Orbassano, TO), Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Italy. PI: Prof. Marina Boido.

Preclinical study of an innovative therapy for neurodegenerative diseases through the transplantation of Neural Stem Cells (NSC) into the nervous system, in particular for Amyotrophic Lateral Sclerosis (ALS).