Neurobiologia clinica

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Gruppo guidato da Antonio Bertolotto

Neurobiologia clinica
Antonio Bertolotto

Antonio Bertolotto

Head physician, Neurologist, S. Luigi Gonzaga Hospital

Contacts:
Tel. + 39 011 9026697
Fax: +39 011 9026 397
mail: antonio.bertolotto@gmail.com

Curriculum
Born in Chiusa di Pesio on 12.2.1952. Italian.
1975-1977: Medical Intern. Division of Neurology, Department of Neuroscience, University of Turin. Mentor: Prof. D. Schiffer
1977: Doctor of Medicine e Surgery cum laude, University of Turin
1977-1981: Resident in Neurology, Division of Neurology, Department of Neuroscience, University of Turin, Turin. Mentor: Prof. D. Schiffer.
1981-1992: Medical Assistant, Division of Neurology, Department of Neuroscience, University of Turin, Turin.
1992-2002: Medical Assistant, Division of Neurology, University Hospital San Luigi Gonzaga, Orbassano, Turin.
2002-2008: head of the Regional Reference Multiple Sclerosis Centre (CReSM) and Clinical Neurobiology, University Hospital San Luigi Gonzaga, Orbassano (Turin).
2009-to date: chairman of the SCDO Neurologia 2 – CreSM (Regional Reference Multiple Sclerosis Centre), University Hospital San Luigi Gonzaga of Orbassano (Turin).

Field of research
Dr Bertolotto's professional interests include clinical studies on drugs immunogenicity, interferon-beta pharmacogenomics and pregnancy in multiple sclerosis and autoimmune diseases.

Membership in research centres:
Neuroscience Institute Cavalieri Ottolenghi (NICO, Turin); Neuroscience Institute Turin (NIT).

Professional organization
American Academy of Neurology (AAN); Italian Society of Neurology (SIN); Associazione Italiana Neuroimmunologia (AINI);Società dei Neurologi, Neurochirurghi e Neuroradiologi ospedalieri (SNO).

Administrative post
Member of the Scientific Committee of the Italian Multiple Sclerosis society (FISM/AISM).
Member of the "Therapeutics and Technology Assessment subcommittee of the American Academy of Neurology" regarding anti-IFN beta antibodies.
Member of the Steering Committee of the Europen NABINMS project [sponsored by the European Union under the Sixth Framework Programme (contract number 018926)]
Chairman of the Piedmont Regional Committee for Multiple Sclerosis (Assessorato alla Sanità).

National and International scientific activity
Grant reviewer for Associazione Italiana Sclerosi Multipla (AISM/FISM); and Istituto Superiore di Sanità.
Reviewer for Annals of Neurology, Neurology, Journal of Neuroimmunology, Multiple Sclerosis, European Neurology, Clinical Chemical Acta, Brain research, Experimental Cell Research, Journal of Interferon & Cytokine Research, Journal Neurology, Neurological Sciences, European Journal of Neurology, Therapeutic Advances in Neurological Disorders, The Pharmacogenomics journal.

Research Grants
Recipient of research grants from the Europen Community; Italian Ministry of Health; Piedmont Region; Associazione Italiana Sclerosi Multipla (AISM/FISM); San Paolo Foundation; Biogen Dompè; Merck-Serono; Sanofi-Aventis.

Didactic Activity
1. 1981-2003 – Lectures on Neurology for medical students, University of Turin.
2. 1980-1995 – Docent of Neurology (40 hours annually) at the School for Specialists in Rehabilitation of Italian Red Cross.
3. 1998 – 2002 - Docent of Neurofisiopathology, lectures on "General Methodology and Techniques for Neuromotor Rehabilitation" for the University Diploma "Physiotherapist".
4. 2002 – 2012 - Docent of "Neurology III", lectures on "General Methodology and Techniques for Neuromotor Rehabilitation" for the University Diploma "Physiotherapist" (17,5 hours, CFU 1).
5. 2003-2012 - Docent of Neurology, lectures on "Neuromotor Rehabilitation" for the course "Techniques of Psychiatric Rehabilitation".
6. 2011-2012 – Docent of Neuromotor Rehabilitation, lectures on "Techniques of Psychiatric Rehabilitation" (18 hours, CFU 1).
7. 2013-2014 – Docent of Neurology, lectures on "Techniques of Psychiatric Rehabilitation" (12 hours, CFS 1), coordinator of the Course on Psychiatric and Neuromotor Rehabilitation".
8. 2008-2009 – Associate Professor, lectures on "Elements of Neuromuscular Pathology" (36 hours), for the course in Exercise Science and Sport, Interfaculty University School in Exercise Science, University of Turin.
9. 3.02.2014 – 2.02.2015 - Tutor for the educational activity of the Specialization School in Neurology
10. 2012-2014 - Tutor of the University Master of the first level in Medical Statistics and Genomics, University of Pavia.
11. 2006 – 2013 - Organizor of 14 residential courses "Everyday management of patient with multiple sclerosis"
12. Docent in Master:
• 2007-2008 - University Master in Equestrian Rehabilitation, University of Turin;
• 2007-2008 – University Master of the first level "Management of the patient with multiple sclerosis for the nurses and physiotherapists", University of Genoa

National and International Congress attended as Invited Speaker:
1. Invited lecturer at the meeting "Management of disability in cronic neurological diseases ." Alba (Italy), 18/04/2009.
2. Invited speaker at the XXV Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) "Neutralizing antibodies to IFNb". Düsseldorf (Germany) 09-12/09/2009.
2. Invited speaker at the Seventh Bioms-eu meeting. Amsterdam (The Netherlands) 31/05/2010.
3. Invited speaker at the meeting "Perspectives and indications for the management of MS center", report on "Mechanisms of physiological action of immunomodulatory drugs in MS" (Turin) 24/10/2011
4. Invited speaker at the meeting "Stratification of risk in patient treated with natalizumab" (Genoa) 11/11/2011.
5. Invited speaker at the meeting at the University of Milan, report on "Farmacological and clinical evolution of the autoimmune disease: MS", 13/11/2012
6. Invited speaker at the meeting at the University of Amsterdam, report on "Anti-drug in Multiple Sclerosis: Detection and Clinical Impact", 17/11/2012
7. Invited speaker at the congress "Best Evidences in Multiple Sclerosis", report on "From process-specific biomarkers to the personalized treatment" (Rome) 11-12/04/2013
8. Invited speaker at the congress "New scenarios in the MS treatment", report on "Organizational aspects of MS Center" (Gallarate) 1/03/2013
9. Invited speaker at the congress "Present e future in the MS Treatment", report on "Management of MS" (Genoa 10/05/2013)
10. Invited speaker at the LIII National Congress SNO, report on "Gender and MS" (Florence) 15-17/05/2013
11. Invited speaker at the congress SIN SNO, report on "New treatment in MS: advantages" (Alba) 13/09/2013
12. Invited speaker at the XLIV Congress SIN "The diagnostic and therapeutic hospital care in the Regional Reference MS Center" (Milan) 2-5/11/2013
13. Invited speaker at the meeting "Neurodegenerative pathologies: integration from research, clinical practice and social impact" - "From research to clinical practice"(Genoa) 13-14/12/2013.
14. Invited speaker at the congress "Appropriateness of natalizumab therapy, reactivation of the disease activity", report on "A new opportunity for more effective treatment" (Bari) 17/01/2014
15. Invited speaker at the meeting "Therapeutic appropriateness" in "Focus on MS: perspective of physician and pharmacist" (Genoa) 07/02/2014
16. Invited speaker at the meeting "Interferon Fundamentals 2014", report on "Biological and clinical monitoring of IFNb in MS" (Rome) 20/02/2014.

Scientific collaborations:

National:
Dr.ssa Aloisi Francesca; Dipartimento di Biologia Cellulare e Neuroscienze, Istituto Superiore di Sanità (ISS), Roma.
Dr. Diego Franciotta; Laboratorio di Neuroimmunologia, IRCCS, Fondazione "Istituto Neurologico C. Mondino", Pavia.
Dr. Roberto Bergamaschi; Dipartimento di Scienze Neurologiche, IRCCS, Fondazione "Istituto Neurologico C. Mondino", Pavia.
Prof. Paolo Gallo; Centro Sclerosi Multipla, Dipartimento di Neuroscienze, I Clinica neurologica, Ospedale universitario di Padova, Padova.
Prof. Francesco Lolli; Prof. Luca Massacesi; Prof.ssa Maria Pia Amato; Dipartimento di Scienze Neurologiche e Psichiatriche, Università degli Studi di Firenze, Firenze.
Dr. Renato Mantegazza; Dr.ssa Graziella Filippini; U.O. Immunologia e Patologia Muscolare Neurologia IV, Istituto Nazionale Neurologico "Carlo Besta" (INNCB), Milano.
Prof. Giancarlo Comi; Divisione di Neurologia e Servizio di Neurofisiologia, Ospedale San Raffaele, Milano.
Dr. Gianvito Martino; Dr. Roberto Furlan; Unità di Neuroimmunologia, Dipartimento di Neuroscienze DIBIT2, Ospedale S. Raffaele, Milano.
Dr. Massimo Filippi; Unità di Neuroimaging Research (NRU), Ospedale S. Raffaele, Milano.
Prof. Marco Salvetti; Centro neurologico terapie sperimentali (Centers), Dipartimento di Scienze Neurologiche, II Facoltà di Medicina e Chirurgia, Università La Sapienza, Roma.
Prof.ssa Maria Trojano; Dipartimento di Scienze Neurologiche e Psichiatriche, Università degli Studi di Bari, Policlinico, Bari.
Prof Gianluigi Mancardi; Prof. Antonio Uccelli; Dipartimento di Neuroscienze, Oftalmologia e Genetica, Università degli studi di Genova, Genova.
Dr. Angelo Grezzi; Dr. Mauro Zaffarono; Centro Sclerosi Multipla, Azienda Ospedaliera S. Antonio Abate, Gallarate (VA).
Prof. Francesco Patti; Centro Sclerosi Multipla, Azienda Ospedaliero-Universitaria "G. Rodolico", Università degli Studi di Catania, Catania.
Prof. Roberto Mutani; Dr.ssa Paola Cavalla; Dipartimento di Neuroscienze, I facoltà di Medicina e Chirurgia, Università degli Studi di Torino, Ospedale Giovanni Battista, Torino.
Prof. Raffaele Calogero; Unità di Bioinformatica e genomica, Dipartimento di Scienze Cliniche e Biologiche, II facoltà di Medicina e chirurgia, Università degli Studi di Torino, AOU S. Luigi Gonzaga, Orbassano (TO).
Prof. Giuseppe Saglio; Divisione di Medicina interna ed Ematologia, Dipartimento di Scienze Cliniche e Biologiche, II facoltà di Medicina e chirurgia, Università degli Studi di Torino, AOU S. Luigi Gonzaga, Orbassano (TO).

International:
Prof. Ludwig Kappos, Prof.ssa Raija Lindberg Department of Research and Neurology, University Hospital Basel (Basel, Switzerland).
Prof. Chris Polman; Dr. Joep Killestein; Dr.ssa Laura van der Voort; Department of Neurology, VU Medical Centre, University of Amsterdam (Amsterdam, The Netherlands)
Dr. C. Teunissen, Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands
Prof. Gavin Giovannoni; Institute of Cell and Molecular Science, Queen Mary University London, Department of Neurology, Barts and The London NHS Trust, The Royal London Hospital (London, UK).
Prof. Florian Deisenhammer; Neuroimmunology Laboratory, Innsbruck Medical University (Innsbruck, Austria)
Prof. Per Soelberg Sørensen, Danish Multiple Sclerosis Research Center, Department of Neurology, Copenhagen University Hospital (Copenhagen, Denmark).
Prof. Jan Hillert; Prof. Anna Fogdell-Hahn; Clinical Neuroscience, Division of Neurology, Karolinska Institutet, Karolinska University Hospital Huddinge (Stockholm, Sweden)
Prof. Huub Schellekens; Central Laboratory Animal Institute, Department of Pharmaceutical Sciences, Department of Innovation Studies, Utrecht University (Utrecht, The Netherlands)
Dr. Arno Kromminga; Immunology - Clinical Pathology - Molecular Medicine, IPM BIOTECH GmbH (Hamburg, Germany).
Prof. Wim Jiskoot; Dr.ssa Miranda van Beers; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University (Utrecht, The Netherlands)
Prof. Joel Oger; Department of Neurology, UBC Hospital, University of British Columbia (Vancouver, Canada)
Prof. Klaus Bendtzen; BioMonitor A/S and CytoMab ApS, Symbion Science Park (Copenhagen, Denmark)
Prof. Andrew Pachner; Department of Neurology and Neurosciences, New Jersey Medical School (NJMS), University of Medicine and dentistry of New Jersey (UMDNJ) (Newark, NJ, USA)?Prof. Eva Havrdová; Dr.ssa Dana Horáková; MS Center, Department of Neurology, Charles University, General Teaching Hospital (Prague, Czech Republic)
Dr.ssa Eva Meluzínová; Dr.ssa Jana Libertinová; Neurologická klinika, FN Motol (Prague, Czech Republic).
Prof. Bernhard Hemmer; Department of Neurology, Klinikum Rechts der Isar, Technische Universitaet Muenchen (Muenchen, Germany).

Publications:

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