GLIAL CELLS-NEURON CROSSTALK IN CNS HEALTH AND DISEASE

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Event date: from 26/02/2020 to 28/02/2020
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GlialCells-Neurons

FEBRUARY 27 th - 29 th , 2020
GLIAL CELLS-NEURON
CROSSTALK IN CNS HEALTH AND DISEASE

University of Turin - Italy
Institute of Anatomy, C.so Massimo D’Azeglio 52

The Workshop is aimed at PhD students and young Postdocs with the goal to promote a thorough understanding of the functions of glial cells in health and disease. The program includes lectures on the newest conceptual advancements and methodological approaches in the study of glial cells in synaptic functions, development and CNS diseases.
The Workshop is based on a series of lectures by renowned international speakers. Participants will have the opportunity to present their own projects and discuss ideas with young experts and established leaders in the field. The program includes sessions devoted to research methodology and theoretical-practical training, that will allow participants to learn and practice state-of-the-art methods to study glia-neuron interactions.

COURSE ORGANIZERS
Valentina Cerrato , Dept. of Neuroscience & NICO, UniTo 
Enrica Boda , Dept. of Neuroscience & NICO, UniTo  
Annalisa Buffo , Dept. of Neuroscience & NICO, UniTo 

PROGRAM in short
Since their discovery, glia were thought for a long time only to support neurons passively. In line with this view, neurological and psychiatric disorders have long been interpreted as the exclusive consequence of abnormalities in neurons. We now appreciate that glia operate as master regulators of numerous aspects of CNS development and plasticity. Further, dysregulations of the glial cells-neuron crosstalk can be primarily involved  in initiation and progression of several neuropathologies. The aim of this 3-day long workshop is to enable participants to get a thorough understanding of the functions of glial cells in health and disease.
The program includes lectures on the newest conceptual advancements and methodological approaches in the study of glial cells in synaptic function, development and CNS disease. Participants will have the opportunity to present their own research projects and discuss ideas with leaders in the field. The program includes sessions devoted to research methodology and theoretical-practical training, that will allow participants to learn and practice state-of-the-art methods/techniques to study glia-neuron interactions.
Credits: 3

SCHEDULE and LOCATION
The workshop will be held on FEBRUARY 27-29, 2020. 
Lectures will take place at the Institute of Anatomy, C.so Massimo D’Azeglio 52, Turin.
The theoretical-practical sessions (day 2) will be held at the Neuroscience Institute Cavalieri Ottolenghi, Regione Gonzole 10, Orbassano (Turin).

REGISTRATION
Deadline for registration: December 23, 2019.
Registration cost for participants: 30 euro. 
The total number of participants will be limited to 60 students, and registrations will be dealt with on a first come, first served basis.  

Go to the registration form  

E-mail addresses for information:  valentina.cerrato@unito.it enrica.boda@unito.it

ABSTRACT SUBMISSION
Deadline for abstracts submission: January 15th, 2020.
A total of six abstracts will be selected for oral communications by the workshop organiziners, while the others will be presented as posters.

PROGRAM

1st day (Feb 27 2020)

  • Beatrice Vignoli (University of Trento, Italy) - Glial microdomains confine a “molecular memory” enabling long-term information storage for memory consolidation
  • Gertrudis Perea (Instituto Cajal, Madrid, Spain) - GABAergic control of Astrocyte-Neuron signaling in cortical circuits
  • Bernadette Basilico (Institute of Science and Technology Austria) - Constitutive role of microglia in maintaining synaptic function in mouse hippocampus
  • Christophe Galichet (Francis Crick Institute, London, UK) – Median Eminence Oligodendrocyte Precursor Cells are required for normal function of the hypothalamo-pituitary axis
  • Marco Perugini (Univ. Milano Bicocca, Italy) - The signal and the noise: Some lessons learned from the replicability crisis in Psychology

2nd day (Feb 28 2020) 

  • Chiara Rolando (Univ. of Basel, Switzerland) - Post-transcriptional regulation of astrocytes: a novel facet to counteract brain aging
  • Rosa Paolicelli (Univ. of Lausanne, Switzerland) - Microglia-mediated synapse loss in neurodegeneration
  • Fabia Filipello (Washington University, St. Louis, USA) - Microglia immune receptor TREM2 in neurodegenerative diseases
  • Chiara Zurzolo (Institut Pasteur, Paris, France) - Roles of Tunneling nanotubes (TNTs) and astrocytes in neurodegenerative diseases
  • Davide De Pietri Tonelli (IIT, Genova, Italy) - Bmal1-dependent control of astrocyte development and function in brain
  • THEORETICAL-PRACTICAL TRAINING: 
    - Tissue clearing and 3D-microscopy mini-course (Miltenyi/LaVision)
    - Magnetic Activated Cell Sorting (MACS) and cytofluorimetric analyses of heterogeneous tissues: principles, simulations, instrument settings and data analysis (Miltenyi

3rd day (Feb 29 2020)

  • Eriola Hoxha (University of Torino, Italy) - Disruption of myelin phospholipid composition impairs action potential conduction in a murine model of Spinocerebellar Ataxia type 38
  • Francesca Boscia (University of Naples, Italy) - Enhancing D-aspartate signaling to promote (re)myelination
  • Nunzio Iraci (University of Catania, Italy) - Exosomes as natural messengers of bioactive molecules in the glial-neuronal signaling in Parkinson’s disease
  • Antonella Consiglio (University of Barcelona, Spain) - Novel insights into Parkinson’s disease through iPSC-based technology
  • Ludovic Telley (University of Lausanne, Switzerland) - Single cell RNA sequencing (scRNAseq) approaches and data analysis
  • Maria Cecilia Angulo (INSERM Paris) - Developmental cell death regulates lineage-related interneuron-oligodendroglia functional clusters and oligodendrocyte homeostasis
  • Enrica Boda (University of Torino, Italy) - Inherent heterogeneity of postnatal oligodendrocyte progenitors: lessons from a microcephaly model
  • Valentina Cerrato (University of Torino, Italy) - The ontogenesis of astrocytes diversity: a remarkably orderly process necessary for the correct cerebellar development and functioning
  • Robert Beattie (Institute of Science and Technology Austria) - Molecular Mechanisms Regulating Gliogenesis in the Neocortex

Program [download pdf]

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Events & Meetings

26 february 2020

GLIAL CELLS-NEURON CROSSTALK IN CNS HEALTH AND DISEASE

University of Turin, Italy   
The Workshop is aimed at PhD students and young Postdocs with the goal to promote a thorough understanding of the functions of glial cells in health and disease. The program includes lectures on the newest conceptual advancements and methodological approaches in the study of glial cells in synaptic functions, development and CNS diseases.

Deadline for registration: December 23, 2019.